Treatment Resistant Depression

When Depression Doesn’t Respond to Treatment, There’s Still Hope.

If you’ve tried two or more antidepressants without meaningful improvement, you may be experiencing treatment-resistant depression (TRD) — and you’re not alone. Up to one-third of people with major depressive disorder face the same challenge. At Prime Psychiatry, we specialize in helping individuals who haven’t found relief from traditional treatments through advanced, evidence-based solutions tailored to your needs.

Innovative Options for Lasting Relief

Our board-certified psychiatric providers take a personalized approach to uncover why previous treatments haven’t worked and explore effective alternatives, including:

  • Spravato® (esketamine): An FDA-approved nasal spray proven to rapidly reduce depressive symptoms in TRD.
  • TMS Therapy: A non-invasive, medication-free option that uses magnetic pulses to stimulate mood-regulating areas of the brain.
  • Customized Medication Plans & Therapy: We optimize medication strategies and integrate psychotherapy to maximize results.

Take the Next Step Toward Feeling Better

Treatment-resistant depression doesn’t mean untreatable depression. Prime Psychiatry offers advanced, effective options to help you move forward. Serving patients across Plano, Frisco, Austin, and Southlake, TX — contact us today to schedule your consultation and explore next-step treatments for depression.

Insurance

Prime Psychiatry accepts most major insurances. Our participation frequently means lower costs for you, as well as a streamlined filing process. We currently accept the following:

Find Out If Our Treatment Resistant Depression Are Right For You